846 LYSOSOMAL AMINO ACID TRANSPORT: DESCRIPTION OF A NEW SYSTEM
نویسندگان
چکیده
منابع مشابه
Cellular uptake of lithium via amino acid transport system A.
We now add to the agencies by which cells take up lithium the process of cotransport with neutral amino acids via System A. In the Ehrlich cell various natural and synthetic amino acids, depending on their structure, can cause substantial accelerations of Li+ uptake over a considerable range of levels of Na+, Li+ and H+. Half the maximal augmentation of uptake, namely 1.2 mequiv. Li/kg cell wat...
متن کاملPlacental amino acid transport.
Normal fetal growth and development depend on a continuous supply of amino acids from the mother to the fetus. The placenta is responsible for the transfer of amino acids between the two circulations. The human placenta is hemomonochorial, meaning that the maternal and fetal circulations are separated by a single layer of polarized epithelium called the syncytiotrophoblast, which is in direct c...
متن کاملAmino Acid Transport
I[I. Place of co-transport with Na ÷ . . . . . . . . . . . . . . . . . . . . . . . . . 489 A. Must the energy for Na+-dependent, uphill amino acid transport be channeled through alkali-metal gradients? . . . . . . . . . . . . . . . . . . . . . . . . . . . 489 B. Attempts to eliminate experimentally the alkali-metal ion gradients without dissipating other forms of transport-related energy storag...
متن کاملPolarized Amino Acid Transport
The transport of three neutral amino acid analogs has been studied in an epithelial cell line from a pig kidney. 2-Aminoisobutyric acid is accumulated by U C PKI cells against a concentration gradient through a mechanism with several features of a carrier-mediated process. The influx is accounted for by a saturable Na+dependent and nonsaturable Na+-independent process. The total influx of 2-(me...
متن کاملDisorders of amino acid transport
S. SEGAL of inherited metabolic diseases such as cystinosis, hereditary Division of Biochemical Development and Molecular Diseases, fructose intolerance and tyrosillaemia, and in most CaSeS is a Children’s Hospital of Philadelphia, and Departments of secondary phenomenon. Taken as a group, amino acid transport Pediatrics and Medicine, university of Pennsyfvania School of abnormalities are among...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1985
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198504000-00876